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YES! Frontline Plus is an extremely effective product for eradicating and preventing fleas, and it remains the UK’s leading flea prevention.*

Frontline Plus combines two active ingredients – Fipronil and S-methoprene. Fipronil targets and kills adult fleas, whilst methoprene is an insect growth regulator that stops eggs and immature fleas from developing into reproducing adults. So it kills-off existing fleas and stops the flea life cycle.

Fipronil has been used on pets since the 1990s and there are no known cases of resistance despite regular testing. Three monthly topical applications of fipronil alone to cats and dogs provided 96.5% flea reductions on animals and the number trapped within homes was reduced 98.6% (1).

Investigations into suspected cases of resistance to fipronil and S-methoprene in fact found the product was more than 98% effective on fleas taken from these dogs. It was therefore concluded that any reported product failures were likely due to other factors but not insecticidal resistance (2).

The most common reason why a treatment can fail is irregular application. Topical fipronil and S-methoprene applied to cats still kills more than 95% of fleas within 24 hours, 28 days after application (3). However, after this time the efficacy does begin to drop, allowing fleas to survive long enough to reproduce. That’s why at Protect My Pet we deliver your flea treatment exactly when it’s due so you never have that problem.

Our friendly customer experience team is always happy to answer your questions and help you choose the best products for your pet. Click here to Contact Us

1. Dryden M.W., Denenberg T.M., Bunch S. Control of fleas on naturally infested dogs and cats and in private residences with topical spot applications of fipronil or imidacloprid. Vet. Parasitol. 2000;93:69–75.

2. Carithers D., Dryden M., Everett W.R., Gross S., Crawford J. Assessment of FRONTLINE® Plus efficacy at 24-hour counts against Tampa 2014 Isolate Ctenocephalides felis flea infestations on cats and dogs on days 1, 7, 14, 21, and 28. Int. J. Appl. Res. Vet. Med. 2018;16:52–58

3. Franc M., Beugnet F., Vermot S. Efficacy of fipronil-(S)-methoprene on fleas, flea egg collection, and flea egg development following transplantation of gravid females onto treated cats. Vet. Ther. 2007;8:285–292

*MAT sales excluding vet channel, market share dashboard July 2020

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